Effect of hepatitis C virus infection on the outcomes of in vitro fertilization.

OBJECTIVE To investigate the impact of Hepatitis C Virus (HCV) infection on in vitro fertilization (IVF) outcomes. METHODS A retrospective analysis was conducted using IVF cases occurring at the Centre for Reproductive Medicine, General Hospital of Tianjin Medical University between January 2008 and December 2013. A total of 1424 couples undergoing IVF cycles were included: Ninety couples where the female was HCV positive, 78 couples where the male was HCV positive, and 1256 control couples where both the male and female were HCV negative by for the presence of HCV RNA and antibodies. RESULTS All experimental and control groups (HCV-positive men, HCV-positive women, and controls) had similar sperm parameters, ovarian stimulation, fertilization and pregnancy results. CONCLUSION HCV infection has no affection on IVF treatment outcomes.